Mix using wooden paddles to avoid warming up the meat. Start by cutting the meat and fat into cubes. How to Make Pepperoni At Home. Nitrate is also added, which gives pepperoni its color. https://www.thespruceeats.com/homemade-pepperoni-recipe-1808542 Chill the grind again before adding the cure and spices. Glad you asked! Salt and sodium nitrate are then added as curing agents, which prevent the growth of unwanted microorganisms. How is pepperoni made? After the meat is trimmed to achieve the proper fat-to-meat ratio it’s finely ground and combined with lactic acid bacteria. Recipes and methods vary, but most pepperoni starts with a mix of pork and beef. Having done this, chill the meat before grinding it. Pepperoni is made from a mixture of ground pork and beef mixed with spices and flavorings. These regulations and rules ensure that any type of cured meat is free from trichinosis contamination. The born-in-America pepperoni is made following strict guidelines laid down by the USDA. In the United States, pepperoni is synonymous with ‘Hormel’, by far the most popular brand in the country.